Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
Referencias:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
All Product Categories
-
Productos relacionados con Drug Intermediate (4742)
Productos relacionados con (4742)
-
Daunomycinone
0 ImagesSynonyms: NSC-109351Daunomycinone (NSC-109351) is a metabolite of Daunomycin (HY-13062A) and anticancer intermediate. Daunomycinone binds to nucleic acids synergistically with metal ions. Daunomycinone can be used in the research of leukemia.
-
1,3-Dibromo-5-methylbenzene
0 Images1,3-Dibromo-5-methylbenzene is an aromatic halide that can be used for the synthesis of other active compounds.
-
Atorvastatin acetonide tert-butyl ester
0 ImagesAtorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
-
5-Amino-2-picoline
0 Images5-Amino-2-picoline (5-Amino-2-methylpyridine) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 5-Amino-2-picoline is also an important intermediate and can be used in the synthesis of other active compounds.
-
(R,S,S,R,S)-Boc-Dap-NE
0 ImagesReferencia número: HY-78931ANo. CAS: 2994330-72-0(R,S,S,R,S)-Boc-Dap-NE is the inactive isomer of Boc-Dap-NE (HY-78931), and can be used as an experimental control. Boc-Dap-NE, is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
-
AFP464 dihydrochloride
0 ImagesReferencia número: HY-16031BPureza: 99.45%Synonyms: NSC710464 dihydrochlorideAFP464 (NSC710464) dihydrochloride is a prodrug of Aminoflavone (HY-132974) and an agonist of the aryl hydrocarbon receptor (AhR). AFP464 dihydrochloride downregulates the expression of α6-integrin (α6-integrin), inhibits breast tumor growth, reduces the population of tumor-initiating cells, disrupts mammosphere structure, induces the formation of mucin lake clusters, triggers DNA damage, and exerts antiproliferative activity. AFP464 dihydrochloride is rapidly converted to Aminoflavone by nonspecific esterases in plasma and cell culture media. AFP464 dihydrochloride is applicable to research related to breast cancer.
-
3,5-Dimethoxybenzoic acid
0 Images3,5-Dimethoxybenzoic acid is an aromatic organic acid and antifungal agent. 3,5-Dimethoxybenzoic acid can also be used as an intermediate for anticancer agents. 3,5-Dimethoxybenzoic acid can be isolated from the leaves of Melia azedarach. 3,5-Dimethoxybenzoic acid exhibits antifungal activity against A. rabiei with an MIC of 0.125 mg/mL. 3,5-Dimethoxybenzoic acid has anti-wrinkle, anti-inflammatory, antioxidant, and skin regeneration effects.
-
2,2-Diethoxyethanol
0 ImagesReferencia número: HY-W010354No. CAS: 621-63-62,2-Diethoxyethanol is a drug intermediate used in research related to Plasmodium falciparum infection.
-
SN-38-CO-DMEDA TFA
0 ImagesSN-38-CO-DMEDA TFA is the intermediate product for synthesizing antibody-conjugated drug LND1035.
-
Prostaglandin A1 ethyl ester
0 ImagesProstaglandin A1 ethyl ester is a prodrug form of Prostaglandin A1. Prostaglandin A1 inhibits the activation of platelets.
-
2-Bromo-3-nitrobenzoic acid
0 Images2-Bromo-3-nitrobenzoic acid is a brominated nitrobenzoic acid and also a starting material for the synthesis of 3-substituted-5-nitroisocoumarins. 3-Substituted-5-nitroisocoumarins are key intermediates of PARP inhibitor analogs. 2-Bromo-3-nitrobenzoic acid serves as an easily accessible precursor for the synthesis of 7-nitrobenzo[b]thiophene and 7-nitro-1,2-benzisothiazole derivatives.
-
γ-Glutamyl-S-(2-carboxypropyl)cysteine TFA
0 ImagesReferencia número: HY-182089APureza: 99.15%γ-Glutamyl-S-(2-carboxypropyl) cysteine TFA is a chemical intermediate. γ-Glutamyl-S-(2-carboxypropyl) cysteine can be used in the synthesis of Alliin (HY-N0661) and Isoalliin (HY-111825A).
-
α-Pinene oxide
0 ImagesReferencia número: HY-W130074No. CAS: 1686-14-2α-Pinene oxide is a type of monoterpene epoxidation intermediate. α-Pinene oxide is produced via the cytochrome P-450-mediated oxidation pathway in Dendroctonus terebrans body microsomes and rat liver microsomes, and can be further converted into alcohols, ketones and insect pheromone derivatives. α-Pinene oxide can generate the perfume intermediate myrtenal. α-Pinene oxide is used in studies related to terpenoid metabolism and perfume synthesis.
-
2,3,5-Trichloropyridine
0 Images2,3,5-Trichloropyridine is a trichloro-substituted pyridine derivative and also serves as an intermediate in the production of herbicidal active substances.
-
4-Hydroxybenzamide
0 Images4-Hydroxybenzamide is an amide and intermediate. 4-Hydroxybenzamide can be isolated from the herb Berberis pruinosa. 4-Hydroxybenzamide derivatives exhibit anti-breast cancer activity. 4-Hydroxybenzamide can be used in atherosclerosis research.
-
Fmoc-Arg(Pbf)-OH-13C6,15N4
0 ImagesReferencia número: HY-Y1636SNo. CAS: 1217461-89-6Fmoc-Arg(Pbf)-OH-13C6,15N4 is the 13C-labeled and 15N-labeled Fmoc-Arg(Pbf)-OH (HY-Y1636). Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis).
-
6-Chloro-7-hydroxy-4-methylcoumarin
0 Images6-Chloro-7-hydroxy-4-methylcoumarin (compound 3) an intermediate of pharmaceutical synthesis.
-
PF-06445974 precursor
0 ImagesPF-06445974 precursor (Compound 28) is a nitro precursor and synthetic intermediate. PF-06445974 precursor can be used for the synthesis of PF-06445974 (HY-119190). PF-06445974 is a positron emission tomography (PET) compound that acts potently on PDE4B.
